Which of the following is NOT a beta-2 long-acting bronchodilator?

The correct answer is Fluticasone HFA, as it is not a beta-2 long-acting bronchodilator. Fluticasone HFA is an inhaled corticosteroid (ICS) used primarily to reduce inflammation in the airways and prevent asthma symptoms. Its primary role is to control asthma long-term by decreasing the frequency of exacerbations, rather than dilating the airways.

In contrast, Formoterol, Salmeterol, and Bitolerol are all classified as long-acting beta-2 adrenergic agonists (LABAs). These medications are designed to relax the muscles surrounding the airways, thereby improving airflow and providing relief from asthma symptoms over an extended period. LABAs are often used in combination with inhaled corticosteroids to provide a comprehensive approach to asthma management, particularly for patients with moderate to severe asthma who require more than just a controller medication.

Understanding the distinctions between these classes of medications is crucial for effective asthma management, as each serves a different therapeutic purpose in controlling the disease.